Well, first off, welcome.
I own a Modified 2001 Lightning and I will tell you this, once you start Modding, it doesnt stop.
Check out my thread '2 MODS of a large list'
I have had my head wrapped around these things for a good couple years now and have done much of the work myself.
The programmer you will want is the SCT xCal 3.
You will want a Catback to make some sound, an Intake, NGK TR6 Plugs and a 4# pulley for daily driver. 6# you will need a MAF extender etc. I would also recommend a FTVB (tranny valve body) to make it shift smooth and chirp the tires.
Regular maintenance is VERY IMPORTANT for these trucks. Consider it a sports car rather than a farm truck.
Fuel filter should be changed every other oil change, don't let your gas tank go below 1/4-1/2. You don't want to starve it of fuel, or go BOOM.
Our rods are the weak link.
Before SLAMMING down on the gas, be sure to turn O/D OFF. Tranny kickdowns can be disasterous.
I will be taking my 4# pulley off if you are interested, I've only had it on for 7,000 kms or so. I will include the belt too.
I live in East End GTA, if you are willing to meet one day, I can show you some stuff if you'd like.
You can run a 'canned' SCT tune with a 4 # pulley and not necessarily need a custom dyno tune yet. You can also Datalog live with a good tuner via email to dial in the tune.
I am headed down in May to get my ported blower, 6 # lower all dyno tuned.
Should be around 440/510 by that point.
Feel free to ask any questions, I live and breath this damn truck.
PS this is my sweetheart